Shinsuke Iida Selected Research

mogamulizumab

10/2022	Genomic determinants impacting the clinical outcome of mogamulizumab treatment for adult T-cell leukemia/lymphoma.
1/2022	Clinical significance of the immunoglobulin G heavy-chain repertoire in peripheral blood mononuclear cells of adult T-cell leukaemia-lymphoma patients receiving mogamulizumab.
11/2021	Phase Ib study on the humanized anti-CCR4 antibody, KW-0761, in advanced solid tumors.
1/2021	Clinical significance of CD28 gene-related activating alterations in adult T-cell leukaemia/lymphoma.
1/2021	Immunohistochemistry for CCR4 C-terminus predicts CCR4 mutations and mogamulizumab efficacy in adult T-cell leukemia/lymphoma.
1/2020	Robust CD8+ T-cell proliferation and diversification after mogamulizumab in patients with adult T-cell leukemia-lymphoma.
1/2019	Mogamulizumab Treatment Elicits Autoantibodies Attacking the Skin in Patients with Adult T-Cell Leukemia-Lymphoma.
1/2018	CCR4 mutations associated with superior outcome of adult T-cell leukemia/lymphoma under mogamulizumab treatment.
12/2015	Fatal reactivation of hepatitis B virus infection in a patient with adult T-cell leukemia-lymphoma receiving the anti-CC chemokine receptor 4 antibody mogamulizumab.
10/2015	Phase Ia Study of FoxP3+ CD4 Treg Depletion by Infusion of a Humanized Anti-CCR4 Antibody, KW-0761, in Cancer Patients.

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Shinsuke Iida Research Topics

Disease

104	Multiple Myeloma 10/2022 - 04/2003
46	Neoplasms (Cancer) 04/2022 - 06/2003
26	Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated) 10/2022 - 09/2003
12	Lymphoma (Lymphomas) 04/2022 - 08/2004
11	Disease Progression 10/2022 - 06/2006
10	Infections 09/2022 - 04/2011
8	Hematologic Neoplasms (Hematological Malignancy) 09/2022 - 06/2003
5	Hepatitis 09/2022 - 06/2010
5	Lymphopenia (Lymphocytopenia) 01/2020 - 11/2015
5	T-Cell Lymphoma (Lymphoma, T Cell) 11/2016 - 08/2004
4	Leukemia 06/2021 - 06/2003
4	Chromosome Aberrations (Chromosome Abnormalities) 12/2020 - 12/2012
4	Neutropenia 01/2020 - 04/2011
3	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 08/2021 - 11/2018
3	Anemia 08/2021 - 11/2015
3	Hypertension (High Blood Pressure) 09/2020 - 03/2016
3	Hepatitis B 05/2020 - 12/2015
3	Thrombocytopenia (Thrombopenia) 01/2020 - 09/2016
3	Stevens-Johnson Syndrome (Lyell's Syndrome) 09/2019 - 05/2013
3	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 07/2019 - 04/2009
3	Hodgkin Disease (Hodgkin's Disease) 05/2018 - 06/2006
3	Monoclonal Gammopathy of Undetermined Significance 01/2018 - 04/2003
3	Mycosis Fungoides 12/2009 - 08/2004
2	Waldenstrom Macroglobulinemia (Macroglobulinemia) 06/2022 - 09/2020
2	Pain (Aches) 02/2022 - 01/2014
2	Pneumonia (Pneumonitis) 12/2021 - 11/2015
2	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2021 - 08/2005
2	Sepsis (Septicemia) 05/2020 - 09/2019
2	Peripheral Nervous System Diseases (PNS Diseases) 10/2019 - 03/2016
2	Fever (Fevers) 08/2019 - 11/2016
2	Blast Crisis (Blast Phase) 07/2019 - 04/2009
2	Cognitive Dysfunction 01/2019 - 01/2018
2	Extranodal NK-T-Cell Lymphoma 12/2018 - 08/2004
2	Exanthema (Rash) 01/2018 - 01/2015
2	Melanoma (Melanoma, Malignant) 01/2014 - 02/2009
2	Philadelphia Chromosome 06/2011 - 04/2009

Drug/Important Bio-Agent (IBA)

36	Dexamethasone (Maxidex)FDA LinkGeneric 10/2022 - 07/2010
28	Bortezomib (Velcade)FDA Link 10/2022 - 11/2008
23	Lenalidomide (CC 5013)FDA Link 10/2022 - 07/2010
20	daratumumabIBA 10/2022 - 10/2017
16	Proteasome InhibitorsIBA 09/2022 - 01/2007
15	Monoclonal AntibodiesIBA 01/2021 - 11/2004
14	mogamulizumabIBA 10/2022 - 03/2010
10	carfilzomibIBA 12/2021 - 03/2016
9	Proteins (Proteins, Gene)FDA Link 10/2019 - 07/2009
8	Melphalan (Alkeran)FDA LinkGeneric 11/2021 - 04/2011
7	Biomarkers (Surrogate Marker)IBA 10/2022 - 01/2015
7	pomalidomideIBA 07/2022 - 01/2015
6	DNA (Deoxyribonucleic Acid)IBA 09/2022 - 06/2010
6	Pharmaceutical PreparationsIBA 01/2021 - 01/2014
6	CCR4 ReceptorsIBA 12/2015 - 08/2004
5	Immunoglobulin G (IgG)IBA 01/2022 - 01/2018
5	Rituximab (Mabthera)FDA Link 01/2021 - 07/2009
5	Prednisolone (Predate)FDA LinkGeneric 01/2021 - 04/2011
5	Messenger RNA (mRNA)IBA 01/2015 - 08/2004
4	Hepatitis B Surface Antigens (HBsAg)FDA Link 09/2022 - 06/2010
4	ixazomibIBA 01/2022 - 01/2018
4	pembrolizumabIBA 08/2021 - 09/2019
4	Immunomodulating AgentsIBA 12/2020 - 04/2015
4	Tryptophan (L-Tryptophan)FDA Link 12/2020 - 06/2015
4	Thalidomide (Thalomid)FDA Link 05/2018 - 04/2009
3	AntibodiesIBA 09/2022 - 03/2011
3	AntigensIBA 09/2022 - 01/2014
3	LigandsIBA 01/2022 - 09/2003
3	Prednisone (Sone)FDA LinkGeneric 11/2021 - 05/2016
3	Dasatinib (BMS 354825)FDA Link 07/2019 - 04/2009
3	Therapeutic UsesIBA 09/2018 - 07/2013
3	ParaffinIBA 05/2018 - 11/2016
3	CCR ReceptorsIBA 06/2006 - 09/2003
2	tirabrutinibIBA 06/2022 - 09/2020
2	AnthracyclinesIBA 04/2022 - 01/2014
2	RNA (Ribonucleic Acid)IBA 01/2022 - 07/2005
2	isatuximabIBA 01/2022 - 12/2020
2	HLA-DRB1 Chains (HLA DRB1)IBA 12/2021 - 02/2014
2	Indicators and Reagents (Reagents)IBA 11/2021 - 12/2018
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 08/2021 - 06/2006
2	Interleukin-2 Receptors (IL 2 Receptor)IBA 08/2021 - 01/2017
2	Phosphotransferases (Kinase)IBA 06/2021 - 12/2012
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 02/2021 - 01/2021
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 04/2011
2	Vincristine (Oncovin)FDA LinkGeneric 01/2021 - 04/2011
2	entecavir FDA Link 06/2020 - 12/2015
2	Amyloid (Amyloid Fibrils)IBA 01/2019 - 01/2016
2	Complement System Proteins (Complement)IBA 01/2019 - 12/2010
2	AutoantibodiesIBA 01/2019 - 10/2015
2	atuveciclibIBA 12/2018 - 01/2017
2	Serine (L-Serine)FDA Link 12/2018 - 06/2004
2	Cyclin-Dependent Kinase 9IBA 12/2018 - 01/2017
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 06/2018 - 12/2014
2	Irinotecan (Camptosar)FDA LinkGeneric 04/2018 - 11/2008
2	Antiviral Agents (Antivirals)IBA 12/2015 - 04/2015
2	Protein Kinases (Protein Kinase)IBA 12/2014 - 10/2005
2	InterleukinsIBA 03/2014 - 06/2006

Therapy/Procedure

44	Therapeutics 10/2022 - 06/2003
22	Drug Therapy (Chemotherapy) 09/2022 - 06/2003
11	Stem Cell Transplantation 09/2022 - 05/2005
7	Hematopoietic Stem Cell Transplantation 10/2019 - 04/2013
6	Immunotherapy 03/2021 - 11/2004
2	Transplantation 01/2022 - 02/2015
2	Aftercare (After-Treatment) 12/2015 - 02/2015